Hasbro has set a precedent the last 2 or 3 years where they showed off exclusive items at Toy Fair so I'm expecting to see a couple of items that fall into that category.
For figures I expect we'll see the EU wave and, if they have exclusives, the boxed Force Unleashed sets for TRU as well as maybe another exclusive figure or two. I think there's a good bet we'll see the first wave of the Fall figures, or at least the packaging for them. We should see any vehicles coming in the Spring so, depending on their plans, I think the Cloud Car and maybe Swamp Speeder and Snowspeeder are good bets.
Probably a couple waves of Clone Wars figures and the Nahdar Vebb mail-away, plus, if Hasbro chooses to mix up the Legacy Collection figs (Clone paint schemes or whatnot) I think we'll see a couple of those. Maybe a handful of new CW Deluxe figures and some Battle Packs...Should be some Galactic Heroes figs along with the new Megabattlers line, and role play items.
There should also be some new, maybe repackaged as well, Transformers and hopefully whatever this Super DLX Vehicle is.
In the presentation they'll probably have another wave or two of CW and Legacy replacement figures, Fall vehicles, more exclusives and if they have anything new for the FX line, it'll probably be shown.