Sounds like Chris Evans
is confirmed for Captain America, with an official announcement coming soon. It also sounds like Weaving is definitely the Red Skull, at least according to this article. It sounds like Evans is signed for three Cap movies, plus Avengers, with possible appearances elsewhere.
I really like Evans as an actor, so I think he could do a good job. However, I do think he was the best part of the Fantastic Four movies, and made the perfect Johnny Storm, and it will be different seeing him in the role of Cap which is/should be completely different. He does seem like a talented actor though - and I've enjoyed him in about every movie we've seen him in, so I won't say he can't pull it off.
I'm curious what our resident Cap fan - Scott - thinks of the casting of this movie so far.