Hindsight is 20-20, but count me in with the "Tired of Inhumans" crowd. I really struggle to comprehend the Marvel U factions that hate on DNA-related super beings, but have no problem with the rest of the Super Heroes. Why would people feel Daisy/Quake is a bigger threat than Hulk or Thor just because she got her powers from her DNA? I would think the average person either just loves or hates all people with powers based on their personal experiences.
I didn't mind the ghost rider stuff, but ditching Mockingbird was a mistake, as was bringing in a different Shield Director. They could have just made the Director Fury and limit his appearances to make him more secretive, or bring in Maria Hill as acting directory like the comics. They've tried to create some of the "is the Director good or bad" mystery and drama with this other guy, but it hasn't played out well in my opinion. I kinda wish they had focused more on working to re-establish Shield and its image with the initial Hydra fallout as well.
That all said, I think they've tackled some pretty cool Marvel U concepts. The LMDs are a neat concept, though in the comics Shield uses them vs. bad guys, and they're super helpful decoys for a variety of spy-guy needs. I liked some of the initial Inhuman stuff, and the various super baddies they've managed to bring in "Madame Hydra, Crusher Creel, etc. I'm still enjoying the show, just not nearly as much as the first few seasons. Hopefully they wrap up the Hydra/LMD/Inhuman stuff this season and move on to something new quickly.