I think we have an idea about the general direction of the season. Both trailers have made it clear that Dr Pershing is going to be released. Seeing Coruscant in a post ROTJ time is interesting, too, because I don't really have a good idea of how Coruscant plays into the whole New Republic era. And that shot in the Disney+ version of the trailer with the dismantling of the Star Destroyer was some great eye candy.
Din Djarin has a quest to go on, that much is clear. And seeing Mandalore in a live action show looks like it's going to be among the high points of the season. The caves seem to be where Din Djarin might redeem himself in the eyes of the Tribe. But Bo-Katan considers them a cult, and hold them responsible for the divisions in Mandalorian society that made them vulnerable to the Empire.
I'm wondering about the Mandalorians in the first few shots. Are they survivors from the Nevarro covert? Ever since the final episode of the first season I have wondered what happened to them. It seemed ambiguous. Were they killed by the Imperial Remnant? Did they shed their armor and flee? Was the Armorer telling the truth about their fate? The series has made it clear that Beskar is extremely valuable, and many in the underworld want it. Did the Armorer kill them for their Beskar? I don't think she's completely clear about her intentions.