I saw this question posted in the latest Mattel Q and A, maybe some encouraging news to the future of MOTU:
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Figures: There's no denying fans want more Masters of the Universe. What would it take for Mattel to bring the toy line back?
Mattel: We ask that fans for just a little bit more patience as we finalize the details. Typically, it takes 12-18 months for toys to go from concept to toy shelf. As for MOTU, we are absolutely working on it.
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I'm kind of hoping that we're getting a new "commemorative" line in the style of the He-Man that was glimpsed at Comic Con. I think I'd probably be in for at least some of that, depending on price/availability and all of that.