I'm not up on the comics, so I have no idea how everything ties together.
They only loosely follow the comic stuff anyway - taking what they like for the MCU and rearranging the rest. Sharon as the Power Broker is a great example of that - its a totally different guy in the comics and I don't think turns bad. Seems a bit out character for her being such a loyal SHIELD agent. I haven't followed modern stuff for several years now, but Sam-Cap sticks around for a long time in the comics (I think he's still the current Cap), so don't expect to see that weird outfit going away. They do bring back Old Man Steve Rodgers for a while (still has his super serum strength and fights in an armored suit). They eventually find a way to make him young again (clone body I think?). I doubt MCU would incorporate any of that, but will be interesting to see what they do with Captain America 4. A film mostly featuring Sam, but with a Chris Evans return would be kind of cool.
Still another six weeks to Loki - that feels like forever!