I think we're just nearing a point of getting a lot of what we want (notice I didn't say most). There's so many repeat figures (Iron Man, Cap, Thing, Hulk, Wolverine, etc.) that it's become tedious to a point.
Space is an issue too. I was cleaning up my little room this weekend (under wifey's direction

) and I have probably 10-20 figures loose in a shopping bag that have no current room for display. With it looking more and more likely we'll move this fall, I'm packing more up than displaying so it's getting quite sad.
But there's still a fair bit I want to get down the road:
-I need to have a vulture, so I'll be buying the next spidey box set

-I still need a Reed Richards and an Invisible woman. I really should have bought the box set I saw in Indy, but didn't because of space issues bringing stuff back. I could sell off my Trenchcoat thing that is still in package and be down to just having a couple of extras

Having the second but rather different Torch would be ok too.
- I need to finish out the Galactus series, getting a piece or two from Scott leaves me only needing one or two
- I'll buy the entire Sentinel series - at least there's a handful of figures I want out of that
- From series 11 I'll probably buy Ultron, Wonder-Man, Scarlet Witch and possibly Task Master, Logan and Vengeance. Not at all sure about the last three, I'll have to see them in person first.
- I'll keep buying spidey villains, like an idiot, so Mysterio for sure, already mentioned vulture but may pass on the crappy blue beetle

And that brings me back to the old refrain:
hey ToyBiz, where the heck is Kingpin? Oh, and She-Hulk
