Yeah, I had some questions, too, some the same as you, McMetal. I only got to the first episode tonight and missed what the point of the ISB meeting. I'll have to rewatch that scene again.
I guess I'm not as attentive as some because Rhydonium has been in Clone Wars, Rebels, Bad Batch and now Andor. Not sure if it matters much to the whole story but with as volatile as it is, it might be why Saw gets the way he does (and bye bye Wil. Man.)
The Dedro-Syril relationship got me thinking. With Syril on Ghorman, is it transactional? Could he just be a pawn in Dedro's game of thrones?
Bix's character is rather tragic so far. She's lost a lot of close people to her, tortured, and almost raped by the Michael Sheen looking Imperial, has PTSD, and now doing drugs. Her plot could end in many ways, but I could see that she potentially becomes a liability and Andor has to make a hard choice (or maybe Luthen has her taken care of, which Cassian then takes him out).
maybe the next 2 episodes explain things?