The only Trek casting I am excited about is Bana (because he is Teh Awesome) and Saldana (just because she is so hot). The rest I really don't know enough about to form an opinion, but on the whole it doesn't appear promising. Shaun of the Dead and the guy from Harold and Kumar?? Come on.
Sinise has been rumored for years, but casting him as "Young Bones" would make no sense because right now he's several years
older than DeForest Kelley was on TOS.

The current rumor I heard was Karl Urban (Eomer in LOTR).