Those are the two I was forgetting - Tombstone and Chameleon. At this point, probably the most well-known Spidey villains that haven't already been done, and I hope we see them eventually. I've seen some indication on the Fwoosh forums that Jesse Falcon has sounded like this Origins lineup out right now might be the majority of the non-movie Spidey stuff we see this year - I guess we'll see how that turns out.
I've also seen a thread on Fwoosh discussing which characters need re-dos in the line, which I think also shows how little there is left to do - besides getting to C-list characters. I'll admit, there are a few I wouldn't mind seeing (Doom, just because I missed him, and maybe the F4 - because aside from Thing, I display the movie versions since the other ones aren't that great), but I know people will complaing once we get "re-dos". The problem is, many of the big guns have pretty nice versions at this point. There are a number of Spideys, plenty of Wolverines/Iron Men, and the recent Face Off figures of Captain America, Daredevil, and the Hulk are pretty darn good (if not perfect). Like I said, I wonder what we'll see next. It seems like (from rumors) we might get into more modern stuff (Astonishing X-Men as one example), so maybe that's where things are headed. We might see more characters like the Winter Soldier, Ronin, etc.
I'm often confused by the whole movie figures issue as well. I'll admit, I often like to pick up the "best" version of many of the movie figures (just from characters/movies I actually care about though), and I know I'll be picking up some of the Spidey 3 movie stuff unless it is incredibly crappy - but like you mentioned Brent, I've never seen a superhero movie line that hasn't been clogging the pegs later on. They must sell a lot of units though, because we keep seeing them. But, there are still Superman Returns figures (tons of them) at Wal-Mart, Target cleared them out (now stocked with the "Man of Steel" continuation line), and I can still find Spidey 2 and Fantastic Four movie figures at TRU. I think there has been some nice figures out of the movie lines (I like the Spidey stuff, and the main Fantastic Four aside from Thing), but it does seem like retailers really go crazy with the stuff. Wal-Mart in particular really seems to like the movie lines, and often dedicate entire aisles to them in our area.